Soracha Dechaumphai, Ph.D.

Lecturer
Soracha.D@chula.ac.th
Profile Summary
 
  • Dedicated academic professional serving as Deputy Dean for Academic and student affairs, Associate Dean for International Affairs, and Principal Investigator specializing in the development of bio-nanomaterials and multifunctional nanoparticle-platform for several pharmaceutical and therapeutic applications such as treatment and diagnostic of infectious diseases and cancers.
  • Established local and international joint research projects to advance interdisciplinary studies.
  • H-index of 26, with over 5,974 citations, reflecting notable impacts and contributions to Nanomedicine.
  • Successfully led the ABET accreditation process for Engineering Programs at Mahidol University, raising international recognition and academic standards for the university.
  • Drove the AUN-QA quality assurance for master and PhD programs, improving the quality of academic and research programs in Biomedical Engineering Graduate Program.
  • Secured and managed research fundings exceeding 8 million baht over 6 years, supporting projects and innovations in the field of Nanomedicine.
  • Implemented and supervised the dual degree MD-MEng program at Faculty of Medicine Ramathibodi hospital and Biomedical Engineering program at Faculty of Engineering, Mahidol University, bridging medical doctor degree and engineering degree.
 


Education


August 2014        Ph.D., Nano Engineering
                            University of California, San Diego, CA, USA                                                
June 2011           M.S., NanoEngineering
                            University of California, San Diego, CA, USA

May 2010            M.E., Biomedical Engineering
                            Colorado State University, CO, USA

March 2006         B.Pharm., Pharmaceutical Sciences (First class honors)
                            Prince of Songkla University, Thailand


 


Invited Talks
 
  • S. Dechaumphai, Nanoparticle biointerfacing by cell membrane cloaking for precision medicine” *Invited Speaker at 38th Southern Biomedical Engineering Conference: New Orleans, LA, 08/2022.
  • S. Dechaumphai, “Biomimetic Nanoparticles for biomedical applications”, *Invited talk at International Conference on Precision Nanomedicine in Theranostics, Taiwan, 10/2021.
  • S. Dechaumphai, “Biomimetic Nanoparticles for infection treatment”, *Invited talk at Fudan University, Shanghai, China, 12/2020.
  • S. Dechaumphai, “Multifunctional theranostic nanoparticles for breast cancer”, *Invited talk at 46th international congress on Science, technology and Technology-based Innovation (STT), Bangkok, Thailand, 10/2020.
  • S. Thamphiwatana, “Biomimetic nanoparticles for cancer theranostics”, *Invited talk at Siriraj Cancer Nanomedicine Conference, Siriraj Hospital, Bangkok, Thailand, 09/2017.
  • S. Thamphiwatana, “Biologically inspired nanoparticles for therapeutic applications” *Invited talk at Department of Biomedical Engineering, Mahidol University, Bangkok, Thailand, 09/2017.
  • S. Thamphiwatana, “Nanoparticle biointerfacing by cell membrane cloaking for precision medicine”, *Invited talk at A Sino-ASEAN Conference on Precision Medicine, Cholburi, Thailand, 06/2017.
  • S. Thamphiwatana, “Biomimetic nanoparticles for infectious treatment and management”, *Invited talk at Biologically Engineering department, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand, 02/2017.
  • S. Thamphiwatana, “Bioinspired nanomedicine for therapeutic applications”, *Invited talk at Biological Sciences department, School of Medicine, Prince of Songkla University, Songkhla, Thailand, 02/2017.
  • S. Thamphiwatana, “Biologically inspired nanomaterials for therapeutic applications”, *Invited talk at Department of Pharmacology, Faculty of Medicine, Mahidol University, Bangkok, Thailand, 12/2016.
  • S. Thamphiwatana, “Biologically inspired nanomedicine for therapeutic applications” 32nd Annual Faculty of Medicine PSU conference: Healthcare in a changing world, Prince of Songkla Universiy, Songkhla, Thailand, 08/2016.
  • S. Thamphiwatana, Gao W, Zhang L. “Hydrogel release of nanoparticle-stabilized liposomes for antimicrobial drug delivery” JSOE 33rd Research Expo, University of California, San Diego, La Jolla, CA, 04/2014.
  • S. Thamphiwatana, “Antimicrobial nanotherapeutics for the treatment of bacterial infection” *Invited talk at Department of Biomedical Engineering, Mahidol University, Bangkok, Thailand, 07/2013.
  • S. Thamphiwatana, Pornpattananangkul D, Gao W, Zhang L. “Antimicrobial nanoparticles for bacterial infection treatment” The 4th International conference on Multi-Functional Materials and Structures, Bangkok, Thailand, 07/2013.
  • S. Thamphiwatana, Fu V, Gao W, Zhang L. “Antimicrobial nanotherapeutics for the treatment of Helicobacter pylori infection”. JSOE 32nd Research Expo, University of California, San Diego, La Jolla, CA, 04/2013.
  • S. Thamphiwatana, Pornpattananangkul D, Fu V, Zhang L. “Gold nanoparticles-stabilized liposomes for bacterial skin infection treatment”. JSOE 31st Research Expo, University of California, San Diego, La Jolla, CA, 04/2012.
 


Selected Publications
 
  • Obonyo M*, Zhang L*, S* Thamphiwatana, Pornpattananangkul D, Fu V, Zhang L. Antibacterial activities of liposomal linolenic acids against antibiotic-resistant Helicobacter pylori, Mol. Pharmaceutics, 2012, 9; 2677-85. (*The authors contributed equally) (IF 4.440)
  • Pornpattananangkul D, Fu V, S. Thamphiwatana, Zhang L, Chen M, Vecchio J, Gao W, Huang CM, Zhang L. In vivo treatment of Propionibacterium acnes infection with liposomal lauric acids, Adv. Healthcare Mater. 2013, 2; 1322-28. (IF 5.760)
  • S. Thamphiwatana, Fu V, Zhu J, Lu D, Gao W, Zhang L. Nanoparticle-stabilized liposomes for pH-responsive gastric drug delivery, Langmuir 2013, 29; 12228-33. (IF 3.833)
  • Banerjee A, S. Thamphiwatana, Carmona EM, Rickman B, Doran K.D, Obonyo M. Deficiency of the myeloid differentiation primary response molecule MyD88 leads to an early and rapid development of helicobacter–induced gastric malignancy, Infect. Immun. 2014, 82; 356-63. (IF 3.731)
  • Gao W, Vecchio D, Li J, Zhu J, Zhang Q, Fu V, S. Thamphiwatana, Zhang L. Hydrogel Containing NanoparticleStabilized Liposomes for Topical Antimicrobial Delivery, ACS Nano 2014, 8; 2900-07. (IF 13.942)
  • Gao W, S. Thamphiwatana, Angsantikul P, Zhang L. Nanoparticle approaches against bacterial infections, WIREs Nanomed. Nanobiotechnol. 2014, 6; 532-47. (IF 4.761)
  • S. Thamphiwatana, Gao W, Pornpattananangkul D, Zhang Q, Fu V, Li J, Li J, Obonyo M, Zhang L. Phospholipase A2-degradable liposomes for antibiotic delivery against Helicobacter pylori, J. Mater. Chem. B 2014, 2, 8201-07. (IF 4.543)
  • S. Thamphiwatana, Gao W, Obonyo M, Zhang L. In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation, Proc. Natl. Acad. Sci. 2014, 111; 17600-05. (IF 9.661)
  • Gao W*, Renfeng D*, S* Thamphiwatana, Jinxing L, Gao W, Zhang L, Wang J. Artificial micromotors in a mouse’s stomach: A step towards in vivo use of synthetic motors, ACS nano 2015, 9; 117-23. (*The authors contributed equally) (IF 13.942)
  • Sung-Woo J, S. Thamphiwatana, Zhang L, Obonyo M. Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori, PLoS ONE 2015, 10; e0116519 (IF 2.806)
  • Gao W, Fang R, S. Thamphiwatana, Luk B, Li J, Angsantikul P, Zhang Q, Hu C.M, Zhang L. Modulating antibacterial immunity via bacterial membrane-coated nanoparticles, Nano. Let. 2015, 26; 443-51. (IF 12.712)
  • Wang F, Gao W, S. Thamphiwatana, Luk B, Angsantikul P, Zhang Q, Hu CM, Fang R, Copp J, Pornpattananangkul D, Lu W, Zhang L. Hydrogel retaining toxin-absorbing nanosponges for local treatment of methicillin-resistant Staphylococcus aureus infection, Adv. Mater. 2015, 27; 3437-43. (IF 19.791)
  • Pang Z, Hu CM, Fang R, Luk B, Gao W, Wang F, Chuluun E, Angsantikul P, S. Thamphiwatana, Lu W, Jiang X, Zhang L. Detoxification of organophosphate poisoning using nanoparticle bioscavengers, ACS nano, 2015, 9; 6450- 58. (IF 13.942)
  • Wu Z, de Avila, BE, Martin A, Christianson C, Gao W, S. Thamphiwatana, Escarpa AQ, Zhang L, Wang J. RBC micromotors carrying multiple cargos towards potential theranostic applications, Nanoscale, 2015, 7; 13680-86. (IF 7.367)
  • Hu CM, Fang R, Wang KC, Luk B, S. Thamphiwatana, Dehaini D, Nguyen P, Angsantikul P, Wen C, Kroll A, Carpenter C, Ramesh M, Qu V, Patel S, Zhu J, Shi W, Hofman F, Chen T, Gao W, Zhang K., Chien S, Zhang L. Nanoparticle biointerfacing by platelet membrane cloaking, Nature 2015, 526; 118-21. (IF 40.137)
  • Angsantikul P, S. Thamphiwatana, Gao W, Zhang L. Cell membrane-coated nanoparticles as an emerging antibacterial vaccine platform, Vaccines 2015, 3; 814-28. (IF 4.422) 
  • Luk B, Fang R, Hu C-M, Copp J, S. Thamphiwatana, Dehaini D, Gao W, Zhang K, Li S, Zhang L. Safe and immunocompatible nanocarriers cloaked in RBC membranes for drug delivery to treat solid tumors, Theranostics 2016, 6; 1004-1011. (IF 8.854)
  • Wang F, Fang R, Luk B, Hu C-M, S. Thamphiwatana, Dehaini D, Angsantikul P, Kroll A, Pang Z, Gao W, Lu W, Zhang L. Nanoparticle-based antivirulence vaccine for the management of mechicillin-resistant Staphylococcus aureus skin infection, Adv. Functional Mater. 2016, 26; 1628-1635. (IF 11.382)
  • Zhang Y, Zhang J, Chen M, Gong H, S. Thamphiwatana, Eckmann L, Gao W, Zhang L. A bioadhesive nanoparticleshydrogel hybrid system for localized antimicrobial drug delivery, ACS Appl. Mater. Interfaces. 2016, 8 (28); 18367- 18374. (IF 7.145)
  • Li J*, S* Thamphiwatana, Liu W*, Esteban-Fernandez de Avila B, Angsantikul P, Sandraz E, Wang J, Xu T, Soto F, Ramez V, Wang X, Gao W, Zhang L, Wang J. Enteric micromotor can selectively position and spontaneously propel in the gastrointestinal tract. (*The authors contributed equally), ACS nano, 2016, 10; 9536-9542. (IF 13.942)
  • Huang Q, Lee J, Arce FT, Yoon I, Angsantikul P, Liu J, Shi Y, Villanueva J, S. Thamphiwatana, Ma X, Zhang L. Nanofibre optic force transducers with sub-piconewton resolution via near-field plasmon–dielectric interactions. Nat. Photonics. 2017, 11 (6); 352-355. (IF 31.169)
  • Li J, Angsantikul P, Liu W, Esteban-Fernández de Ávila B, S. Thamphiwatana, Xu M, Sandraz E, Wang X, Delezuk J, Gao W, Zhang L. Micromotors Spontaneously Neutralize Gastric Acid for pH-Responsive Payload Release. Angew. Chem. Int. Ed. 2017, 56 (8); 2156-2561. (IF 11.994)
  • de Ávila BE, Angsantikul P, Li J, Lopez-Ramirez MA, Ramírez-Herrera DE, S. Thamphiwatana, Chen C, Delezuk J, Samakapiruk R, Ramez V, Zhang L. Micromotor-enabled active drug delivery for in vivo treatment of stomach infection. Nat. Commun. 2017, 8; 272. (IF 12.124)
  • S. Thamphiwatana, Angsantikul P, Escajadillo T, Zhang Q, Olson J, Luk BT, Zhang S, Fang RH, Gao W, Nizet V, Zhang L. Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management. Proc. Natl. Acad. Sci. 2017, 114; 11488-93. (IF 9.661)
  • Angsantikul P, S. Thamphiwatana, Zhang Q, Spiekermann K, Zhuang J, Fang R, Gao W, Obonyo M, Zhang L. Coating nanoparticles with gastric epithelial cell membrane for targeted antibiotic delivery against Helicobacter pylori infection. Adv. Therapeutics. 2018, 201800016. (IF 5.20)
  • S. Thamphiwatana, Phairatana T, Chirasatitsin S, Samae M, Casquillas G, Al-Salami H, Kojić S, Stojanović G. A microfluidic micromixer fabricated using polydimethylsiloxane-based platform for biomedical applications. Informacije MIDEM. 2018, 48 (3); 173-180.
  • Zhu Y, Yu X, SD. Thamphiwatana, Zheng Y, Pang Z. Nanomedicines modulating tumor immunosuppressive cells to enhance cancer immunotherapy. Acta Pharmaceutica Sinica B. 2020 Aug 27. (IF 7.097)
  • Marshall SK, Angsantikul P, Pang Z, Nasongkla N, Hussen RS, SD. Thamphiwatana. Biomimetic Targeted Theranostic Nanoparticles for Breast Cancer Treatment. Molecules. 2022 Oct 1;27(19):6473. (IF 4.927)
  • Ma B, Liu X, Zhang Z, Ma C, Chand R, Patwardhan S, Wang C, SD. Thamphiwatana, Chen P, Chen W. A digital nanoplasmonic microarray immunosensor for multiplexed cytokine monitoring during CAR T-cell therapy from a leukemia tumor microenvironment model. Biosensors and Bioelectronics. 2023 Mar 24:115247. (IF 12.545)
 


Grants


2024-2025           Principal investigator. Renal-targeted nanodelivery for
                            diabetic nephropathy therapy
2023-2025           Co-investigator. Microneedle transdermal transport study
                            of pramipexole dihydrochloride for the treatment of
                            Parkinson’s disease
2019-2023           Co-Principal investigator. Development of Kratom extract
                            delivery system through nanotechnology together with
                            microneedle patch for chronic pain management
2020-2022           Principal investigator. Nanotherapeutics against
                            Carbapenems-resistant Enterobacteriaceae (CRE) and
                            its Biofilm
2020-2022           Principal investigator. pH-responsive nanoparticles for
                            dual actions against antibiotic-resistant infection
2019-2021           Principal investigator. Multifunctional theranostic
                            nanoparticles for the treatment and detection of
                            colorectal cancer.
2019-2020           Co-Principal investigator. Feasibility of the first scaled up
                            nanoparticle synthesis for antimicrobial resistant infection
                            treatment (NANOSYN).
2019-2020           Principal investigator. Nanoparticles-enabled
                            multifunctional surface coating on orthopedic implants
                            for the treatment and prevention of biomaterial-
                            associated infection.
2018-2020           Principal investigator. Multivalent nanoparticles-enabled
                            microfluidic device for circulating tumor cells isolation and
                            detection.
2017-2018           Principal investigator. Nanoparticles-embedded
                            microneedle array patch for anti-aging treatment.
2017-2019           Co-investigator. Cost-effective microfluidic electronic
                            devices for optimal drug administration based on
                            fractional pharmacokinetics for leukemia treatments
                            (MEDLEM)
2017-2018           Principal investigator. Red blood cells membrane cloaked
                            nanoparticles for dual actions of toxin binding and killing
                            methicillin-resistance Staphylococcus aureus (MRSA).
 


Patents
 
  • Zhang, L.; Hu, C-M.; Fang, R.; Luk B.; Thamphiwatana S. “Treating infection by platelet-targeting microbe using nanoparticles”, United States patent US 11,224,577. 2022 Jan 18.
  • นางสาวดิษยา พรพัฒนนางกูร และ นางสาวสรชา ธรรมภิวัฒนา. สูตรผสมอนุภาคนาโนของกรดไขมันและกรรมวิธีการผลิตสูตรผสมดังกล่าว, เลขที่ F คําขอ 1701006284
  • นางสรชา เดชะอําไพ และ นางสาวต้องหทัย ไพรัตน์. อุปกรณ์ไมโครฟลูอิดิกส์ (Herringbone), เลขที่ F คําขอ 2102004051
  • นางสรชา เดชะอําไพ และ นางสาวต้องหทัย ไพรัตน์. อุปกรณ์ไมโครฟลูอิดิกส์ (Micropost), เลขที่ F คําขอ 2102004052